What Can I Compare With The Pep Nation Lab Comparison Tool?

Any research-grade compound in the library can be placed side by side - up to four at a time. The tool compares mechanism of action, molecular target, evidence tier, molecular weight, amino acid sequence, reported half-life, and what each compound has been studied for, all drawn from referenced monographs.

What Does The Evidence Tier Mean?

The evidence tier reflects how extensively a compound has been studied in the referenced literature, from early preclinical signals through to compounds with human clinical data. It is a research-quality signal only, never a safety or efficacy endorsement.

How Are "X vs Y" Comparison Pages Built?

Each comparison page is generated from the same referenced compound database - a genuine side-by-side of mechanism, identity, pharmacokinetics, and evidence, plus data-derived key differences. They are curated, not auto-generated thin pages.

Is Any Of This Medical Or Dosing Advice?

No. Every comparison is for in vitro laboratory research use only. Nothing here is medical advice, a treatment recommendation, or dosing guidance, and no product is for human or animal consumption.

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2/4

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SemaxA93

CerebrolysinA94

Top Pick: CerebrolysinTap to see full verdict & analysis

Semax

0/100

Grade A

Leads in safety profile

Evidence

Safety

Science

Coverage

Handling

Depth

Unique: Immune

Cerebrolysin

0/100

Grade A

Leads in evidence strength

Evidence

Safety

Science

Coverage

Handling

Depth

Unique: Healing & Recovery

Research Profile Radar - hover axes for details

Semax

Cerebrolysin

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Attribute	Semax A	Cerebrolysin A
Research Summary	Semax is like a heavy cup of coffee for your brain but without the jitters. Originally developed in Russia, it sharpens your focus, improves your memory, and protects your brain from stress.	Cerebrolysin is like plant food for your brain. It helps broken brain cells heal after an injury (like a stroke or a hard hit) and helps healthy brain cells grow new connections so you can think clearer.
Studied For	Ischemic stroke recoveryCognition / memory enhancementOptic nerve disordersCNS disorders researchADHD researchBDNF upregulationNeuroprotectionAnxiety reductionDepression modelsTransient ischemic attack (TIA) modelsSerotonin upregulationDopamine enhancementFocus and attention researchImmune modulationMelanocortin system cognitive effectsNeurogenesis researchPost-stroke cognitive improvementbrain fogcognitive enhancementADHDstroke recoveryneuroprotectionmemory improvementBDNF increasefocus	Acute ischemic stroke recoveryTraumatic brain injury (TBI)Vascular dementiaAlzheimer's-type dementiaCognitive impairment recoveryNeuroprotectionNeuroregenerationBDNF and NGF pathway stimulationPost-stroke rehabilitationParkinson's disease researchADHD researchMemory enhancementAnti-apoptotic neuronal protectionNeuroplasticity promotionSpine injury modelsCerebral ischemia protectionAge-related cognitive declineTBI recoveryAlzheimer's researchdementianeurogenesisstroke recoverycognitive declineneurological repair
Research Areas	CognitiveImmuneLongevity	CognitiveHealing & RecoveryLongevity
Best Stacked With	selankpinealoncerebrolysinnad-plusbac-water	semaxselankpinealonnad-plus
Overview
Category	Immunity & Wellness	Immunity & Wellness
Compound Class	Synthetic heptapeptide analog of ACTH 4-7 with Pro-Gly-Pro extension; neuroprotective and nootropic	Porcine brain-derived standardized peptide hydrolysate (<10 kDa peptides); neurotrophic factor mimetic
Molecular Target	Melanocortin receptors (MC2R/MC4R); BDNF/NGF upregulation; serotonin/dopamine axis; enkephalinase inhibition	BDNF/TrkB pathway; NGF/TrkA pathway; anti-apoptotic (Bcl-2 upregulation); antioxidant; glutamate excitotoxicity protection
Aliases / AKA	Semax peptideACTH 4-7 PGPMet-Glu-His-Phe-Pro-Gly-ProSemax nasal sprayACTH analog nootropicHeptapeptide nootropic	FPF-1070Cerebrolysin injectionPorcine brain peptide hydrolysateBrain peptide mixtureNeurotrophic peptide mixtureEVER Neuro Pharma cerebrolysin
Parent Compound	ACTH(4-10) fragment	Porcine brain proteins
Molecular Weight	813.9 Da	mixture
Amino Acid Sequence	`Met-Glu-His-Phe-Pro-Gly-Pro`	`standardized peptide mixture (<10 kDa)`
CAS Number	80714-61-0	not applicable
Year Discovered	Not Listed	Not Listed
Pro-Angiogenic	No	No
GLP-1 Class	No	No
Purity	Not Listed	Not Listed
Identity
Evidence Tier
Risk Level
PubMed Citations	314 Good	2,579 Extensive
Clinical Trials	Not Listed	2323 Active
Regulatory Status	Registered in Russia; not FDA or EMA approved.	Approved in many EU/Asia/CIS countries; not FDA-approved.
Evidence & Regulatory
Half-Life	~5 minutes	~20-30 minutes
Typical Frequency	Not Listed	Not Listed
Administration Route	Injection Only	Injection Only
Mechanism / PK	Not Listed	Not Listed
Reported Findings	Russian use and studies report benefit in stroke and cognition. Animal data show neuroprotection and improved learning. Predominantly Russian-literature and preliminary.	Approved in many countries for stroke, TBI, and dementia. Trial evidence is mixed: some subgroup benefits, but a large stroke trial was negative and a 2020 Cochrane review found insufficient evidence in acute ischemic stroke.
Side Effects Noted	Reported well tolerated; intranasal local irritation; limited independent adverse-event data.	Generally tolerated; injection-site reactions, dizziness, agitation, sweating; theoretical porcine allergy.
Warnings	Thin, geographically concentrated evidence; registered in Russia but not FDA or EMA approved. Research use only elsewhere.	Contraindicated in hypersensitivity, status epilepticus, and severe renal impairment per foreign labeling. Not FDA-approved.
Pharmacology
Form	lyophilized	sterile aqueous solution (not lyophilized)
Diluent	bacteriostatic water	used as-is
Storage Temp	frozen, dark	protect from light
Light Sensitive	Yes	Yes
Freeze / Thaw	avoid	n/a
Handling Notes	Often studied as an intranasal formulation.	Do not co-infuse with amino-acid solutions; batch variability.
Reconstituted Shelf Life	28 Days Refrigerated	Not Listed
Handling & Storage

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