Epithalon
Also Known As: Epitalon, Epithalamin, Ala-Glu-Asp-Gly, AEDG peptide, Epithalon tetrapeptide, Pineal peptide bioregulator, Epithalamine, Khavinson peptide, Telomere elongation peptide, Anti-aging tetrapeptide, Epithalon 10mg, Epitalon peptide, pineal gland peptide, telomerase activator, epithalamin, AGAG, anti-aging
Epithalon is a research-grade Synthetic tetrapeptide bioregulator derived from pineal gland epithalamin targeting Telomerase activation studied in Anti-Aging & Longevity research. It is supplied strictly for in vitro laboratory research use only - not for human or animal consumption, and not FDA-approved.
Evidence Tier: Research Compound - No approved human use; sold for laboratory research only.
A short pineal-derived peptide studied for telomere and aging biology. Evidence is mostly cell-culture and animal; human data are preliminary.
At A Glance
| Category | Anti-Aging & Longevity |
|---|---|
| Compound Class | Synthetic tetrapeptide bioregulator derived from pineal gland epithalamin |
| Molecular Target | Telomerase activation (TERT); pineal melatonin synthesis; antioxidant enzyme upregulation |
| Molecular Weight | 390.35 Da |
| Amino Acid Sequence | Ala-Glu-Asp-Gly (AEDG) |
| CAS Number | 307297-39-8 |
| Half-Life | ~10-15 minutes |
| WADA Status | not_listed |
| Evidence Tier | Research Compound |
Mechanism Of Action
It wakes up an enzyme called telomerase. This enzyme physically adds length back to the ends of your chromosomes (telomeres), which extends the lifespan of the cell.
Studied For
- Telomere elongation
- Anti-aging / longevity
- Circadian rhythm regulation
- Antioxidant defense
- Melatonin production stimulation
- Pineal gland restoration
- Immune system enhancement in aging
- Lifespan extension models
- Cancer prevention research
- DNA repair
- Neuroendocrine system regulation
- Oxidative stress reduction
- Age-related disease prevention
- Sleep quality via melatonin
- Skin anti-aging
- Retinal cell protection
- Inflammatory cytokine modulation
- longevity
- anti-aging
- sleep regulation
- life extension
- circadian rhythm
- melatonin production
- telomere lengthening
- antioxidant
Reported Research Findings
In vitro work in human fibroblasts reported induced telomerase activity and telomere elongation. Animal data show antioxidant and antitumor signals. Human evidence is limited, old, and from a single research group, so it is preliminary.
Safety And Handling Notes
No well characterized adverse-event profile; reported well tolerated in sparse low-quality studies. Theoretical concern that telomerase upregulation could favor proliferation of malignant cells.
Not approved anywhere; thin, non-independent human evidence. Research use only.
Regulatory Status
Not FDA or EMA approved; research chemical only.
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