Pinealon vs Epithalon: Research Comparison
A Side-By-Side Research Comparison Of Pinealon And Epithalon - two peptide bioregulators studied in longevity and neuro research. This Reference Compares Mechanism, Evidence Tier, Molecular Identity, And Pharmacokinetics For Qualified Researchers. For In Vitro Laboratory Research Use Only. Not Medical Advice Or Dosing Guidance.
Side-By-Side Comparison
| Pinealon | Epithalon | |
|---|---|---|
| Category | Anti-Aging & Longevity | Anti-Aging & Longevity |
| Compound Class | Synthetic tripeptide bioregulator (Glu-Asp-Arg) derived from pineal gland peptide complex | Synthetic tetrapeptide bioregulator derived from pineal gland epithalamin |
| Evidence Tier | Research Compound | Research Compound |
| Molecular Target | Epigenetic regulation of neuronal genes; antioxidant enzyme induction; serotonin/melatonin pathway modulation | Telomerase activation (TERT); pineal melatonin synthesis; antioxidant enzyme upregulation |
| Molecular Weight | 418.41 Da | 390.35 Da |
| Amino Acid Sequence | Glu-Asp-Arg (EDR) | Ala-Glu-Asp-Gly (AEDG) |
| CAS Number | 175175-23-2 | 307297-39-8 |
| Half-Life | ~5-10 minutes | ~10-15 minutes |
| Studied For | Neuroprotection, Neuronal aging, Cognition / memory research, Retinal cell neuroprotection | Telomere elongation, Anti-aging / longevity, Circadian rhythm regulation, Antioxidant defense |
About Pinealon
A short pineal-lineage peptide studied for neuroprotection and brain aging in cell and animal models.
Read The Full Pinealon MonographAbout Epithalon
A short pineal-derived peptide studied for telomere and aging biology. Evidence is mostly cell-culture and animal; human data are preliminary.
Read The Full Epithalon MonographKey Differences
- Reported half-life differs: Pinealon at ~5-10 minutes versus Epithalon at ~10-15 minutes.
- Primary molecular target differs: Pinealon acts on Epigenetic regulation of neuronal genes; antioxidant enzyme induction; serotonin/melatonin pathway modulation; Epithalon acts on Telomerase activation (TERT); pineal melatonin synthesis; antioxidant enzyme upregulation.
Continue Researching
This Comparison Is Provided For In Vitro Laboratory Research Use Only. Not For Human Consumption, Diagnosis, Or Treatment. See The Full Research Disclaimer.