Pinealon
Also Known As: EDR, Glu-Asp-Arg, Pinealon peptide, EDR tripeptide, Neuroprotective tripeptide, Pineal bioregulator, Khavinson pineal peptide, Glutamyl aspartyl arginine, EDR bioregulator, Brain peptide bioregulator, Neuronal aging peptide, Pineal gland peptide, pineal peptide, bioregulator, short peptide
Pinealon is a research-grade Synthetic tripeptide bioregulator targeting Epigenetic regulation of neuronal genes studied in Anti-Aging & Longevity research. It is supplied strictly for in vitro laboratory research use only - not for human or animal consumption, and not FDA-approved.
Evidence Tier: Research Compound - No approved human use; sold for laboratory research only.
A short pineal-lineage peptide studied for neuroprotection and brain aging in cell and animal models.
At A Glance
| Category | Anti-Aging & Longevity |
|---|---|
| Compound Class | Synthetic tripeptide bioregulator (Glu-Asp-Arg) derived from pineal gland peptide complex |
| Molecular Target | Epigenetic regulation of neuronal genes; antioxidant enzyme induction; serotonin/melatonin pathway modulation |
| Molecular Weight | 418.41 Da |
| Amino Acid Sequence | Glu-Asp-Arg (EDR) |
| CAS Number | 175175-23-2 |
| Half-Life | ~5-10 minutes |
| WADA Status | not_listed |
| Evidence Tier | Research Compound |
Mechanism Of Action
It is a short peptide that interacts directly with DNA in brain cells, regulating the production of proteins that protect neurons from oxidative stress and programmed cell death.
Studied For
- Neuroprotection
- Neuronal aging
- Cognition / memory research
- Retinal cell neuroprotection
- Ischemia-induced brain damage models
- Parkinson's research
- Age-related cognitive decline
- Sleep regulation via pineal
- Circadian rhythm support
- DNA oxidative damage protection
- Brain antioxidant research
- Glaucoma / ocular neurodegeneration research
- Longevity via neuroprotection
- Stress-induced neurotoxicity models
- brain health
- circadian rhythm
- cognitive function
- memory
- anti-aging
- neurological repair
Reported Research Findings
In vitro and rodent studies report reduced oxidative stress and neuroprotection. No robust independent human data. Preliminary.
Safety And Handling Notes
No characterized human adverse-event profile; reported tolerable in limited preclinical work.
Not approved; preliminary, single-lineage evidence. Research use only. Identity resolved 2026-08-04: Pinealon (EDR, Glu-Asp-Arg) is CAS 175175-23-2, C15H26N6O8, 418.41 Da.
Regulatory Status
Not FDA or EMA approved; research chemical.
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