DSIP
Also Known As: Delta Sleep-Inducing Peptide, DSIP peptide, Delta sleep peptide, DSIP neuropeptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, Sleep peptide, Endogenous sleep modulator, Neuropeptide sleep, Delta-wave sleep peptide, DSIP nonapeptide, sleep peptide
DSIP is a research-grade Endogenous neuropeptide targeting Hypothalamic receptors studied in Immunity & Wellness research. It is supplied strictly for in vitro laboratory research use only - not for human or animal consumption, and not FDA-approved.
Evidence Tier: Research Compound - No approved human use; sold for laboratory research only.
A sleep-related peptide with an unconfirmed mechanism and weak, dated human evidence.
At A Glance
| Category | Immunity & Wellness |
|---|---|
| Compound Class | Endogenous neuropeptide (9 amino acids) produced in hypothalamus |
| Molecular Target | Hypothalamic receptors; modulates GH, LH, corticosteroid release; delta-wave EEG promotion |
| Molecular Weight | 848.8 Da |
| Amino Acid Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
| CAS Number | 62568-57-4 |
| Half-Life | ~15 minutes |
| WADA Status | not_listed |
| Evidence Tier | Research Compound |
Mechanism Of Action
It calms down the brain's stress signals and promotes a specific type of brain wave (Delta waves) that only happens during the most restorative phase of deep sleep.
Studied For
- Sleep research
- Delta-wave sleep promotion
- Sleep onset latency reduction
- Insomnia research
- Stress modulation
- HPA axis regulation
- Hypothalamic regulation
- Cortisol regulation
- Pain modulation
- Opiate withdrawal research
- Circadian rhythm support
- Antioxidant neuroprotection
- Neuropeptide signaling research
- LH/GH sleep pulsatility
- REM sleep research
- Sleep architecture optimization
- deep sleep
- insomnia
- stress reduction
- sleep quality
- pain relief
- LH regulation
Reported Research Findings
Animal studies report EEG delta induction and anti-stress effects. Human data are limited, dated, and inconsistently reproduced. Weak.
Safety And Handling Notes
Sparse safety data; reportedly low toxicity in early work; poorly characterized.
Unconfirmed mechanism and no robust modern trials; rapidly degraded. Research use only.
Regulatory Status
Not approved anywhere; research chemical.
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