Selank vs DSIP: Research Comparison
A Side-By-Side Research Comparison Of Selank And DSIP - an anxiolytic nootropic versus a sleep-associated research peptide. This Reference Compares Mechanism, Evidence Tier, Molecular Identity, And Pharmacokinetics For Qualified Researchers. For In Vitro Laboratory Research Use Only. Not Medical Advice Or Dosing Guidance.
Side-By-Side Comparison
| Selank | DSIP | |
|---|---|---|
| Category | Immunity & Wellness | Immunity & Wellness |
| Compound Class | Synthetic heptapeptide anxiolytic / nootropic; tuftsin analog (Thr-Lys-Pro-Arg-Pro-Gly-Pro) | Endogenous neuropeptide (9 amino acids) produced in hypothalamus |
| Evidence Tier | Research Compound | Research Compound |
| Molecular Target | Enkephalinase inhibition; GABA-A receptor modulation; BDNF upregulation; serotonin/dopamine pathway; T-cell tuftsin receptor | Hypothalamic receptors; modulates GH, LH, corticosteroid release; delta-wave EEG promotion |
| Molecular Weight | 751.88 Da | 848.8 Da |
| Amino Acid Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
| CAS Number | 129954-34-3 | 62568-57-4 |
| Half-Life | ~2 minutes | ~15 minutes |
| Studied For | Generalized anxiety disorder research, Stress modulation, Cognition / attention / focus, Memory enhancement | Sleep research, Delta-wave sleep promotion, Sleep onset latency reduction, Insomnia research |
About Selank
A calming, nootropic peptide used in Russia for anxiety; Western evidence is thin.
Read The Full Selank MonographAbout DSIP
A sleep-related peptide with an unconfirmed mechanism and weak, dated human evidence.
Read The Full DSIP MonographKey Differences
- Reported half-life differs: Selank at ~2 minutes versus DSIP at ~15 minutes.
- Primary molecular target differs: Selank acts on Enkephalinase inhibition; GABA-A receptor modulation; BDNF upregulation; serotonin/dopamine pathway; T-cell tuftsin receptor; DSIP acts on Hypothalamic receptors; modulates GH, LH, corticosteroid release; delta-wave EEG promotion.
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This Comparison Is Provided For In Vitro Laboratory Research Use Only. Not For Human Consumption, Diagnosis, Or Treatment. See The Full Research Disclaimer.