CJC-1295 With DAC

Also Known As: CJC-1295 DAC, CJC 1295 with DAC, CJC1295 DAC, GHRH analog with DAC, CJC-1295 Drug Affinity Complex, DAC-GRF, Modified GHRH long-acting, CJC 1295 extended release, CJC-1295 albumin-binding GHRH, Long-acting GHRH analog, Growth hormone releasing hormone analog DAC, CJC1295 with drug affinity complex, CJC with DAC, Drug Affinity Complex, long acting GHRH

CJC-1295 With DAC is a research-grade Long-acting synthetic GHRH analog with Drug Affinity Complex targeting GHRH receptor studied in Muscle Growth & Performance research. It is supplied strictly for in vitro laboratory research use only - not for human or animal consumption, and not FDA-approved.

Evidence Tier: Research Compound - No approved human use; sold for laboratory research only.

A long-acting growth-hormone-releasing peptide; banned in sport.

At A Glance

CJC-1295 With DAC Key Research Facts
CategoryMuscle Growth & Performance
Compound ClassLong-acting synthetic GHRH analog with Drug Affinity Complex (DAC) albumin-binding moiety
Molecular TargetGHRH receptor (GHRHR) on pituitary somatotrophs; sustained GH and IGF-1 elevation
Molecular Weight3647.1 Da
Amino Acid Sequencetetrasubstituted GRF(1-29) + DAC
CAS Number446262-90-4
Half-Life~6-8 days (albumin-bound, DAC)
WADA Statusprohibited
Evidence TierResearch Compound

Mechanism Of Action

It attaches to a larger protein in your blood (albumin), which stops your body from destroying it quickly. This allows it to constantly knock on the pituitary gland's door to release growth hormone for days.

Studied For

  • GH pulsatile release research
  • GH-axis anti-aging
  • Growth hormone deficiency
  • Extended GH secretion
  • Anti-aging / longevity via GH axis
  • Muscle growth via GH axis
  • Body composition improvement
  • Fat reduction via GH
  • Sleep quality enhancement
  • IGF-1 elevation research
  • Recovery and repair via GH axis
  • Bone density via GH stimulation
  • Collagen synthesis via GH axis
  • Metabolic rate increase
  • Adult GH deficiency models
  • GH secretagogue research
  • continuous GH release
  • muscle growth
  • fat loss
  • IGF-1 elevation
  • recovery

Reported Research Findings

A 2006 human Phase 1/2 study showed single doses raised growth hormone for about 6 days and IGF-1 for 9 to 11 days. Limited evidence beyond early trials.

Safety And Handling Notes

Injection-site reactions, facial flushing, headache, water retention. Sustained non-pulsatile growth-hormone elevation raises a theoretical desensitization concern.

Not approved; no chronic-use safety data; general growth-hormone-axis risks apply. WADA-prohibited. Research use only.

Regulatory Status

Not FDA-approved; research chemical; WADA S2.

Full Reference Detail

Related Research Guides

Maintained By The Pep Nation Lab Research Team. See Our Editorial Standards And Research Methodology For How This Reference Is Sourced And Reviewed.

This Reference Is Provided For In Vitro Laboratory Research Use Only. Not For Human Consumption. See The Full Research Disclaimer.

References And Citations

  1. PubMed / NCBI Reference
  2. en.wikipedia.org
Spec Sheet

CJC-1295 With DAC

Also Known As: CJC-1295 DAC, CJC 1295 with DAC, CJC1295 DAC, GHRH analog with DAC, CJC-1295 Drug Affinity Complex, DAC-GRF, Modified GHRH long-acting, CJC 1295 extended release, CJC-1295 albumin-binding GHRH, Long-acting GHRH analog, Growth hormone releasing hormone analog DAC, CJC1295 with drug affinity complex, CJC with DAC, Drug Affinity Complex, long acting GHRH

Research CompoundMuscle Growth & Performance

Explain Like I'm 5

  • CJC-1295 with DAC is a messenger that tells your brain to release more growth hormone. The "DAC" part acts like a super-glue, making the messenger stick around in your blood for a whole week instead of disappearing quickly.

A long-acting growth-hormone-releasing peptide; banned in sport.

Identity & Classification
CJC-1295 With DAC Key Research Facts
ClassLong-acting synthetic GHRH analog with Drug Affinity Complex (DAC) albumin-binding moiety
Molecular TargetGHRH receptor (GHRHR) on pituitary somatotrophs; sustained GH and IGF-1 elevation
CategoryMuscle Growth & Performance
Molecular Weight3647.1 Da
Amino Acid Sequencetetrasubstituted GRF(1-29) + DAC
CAS Number446262-90-4
Parent CompoundGrowth hormone releasing factor
Research Metrics at a Glance
2
PubMed Citations
1
Clinical Trials
1 Active

Related Compounds

Research Use Only. Not For Human Or Veterinary Use. Information Provided For Laboratory Research Purposes Only.

Research Reference Only — Not Medical Advice. For In Vitro Laboratory Use Only.
Typical Dose1–2 mg per week
FrequencyOnce or twice weekly
Cycle On8–12 weeks
Cycle Off4 weeks
Route(s)
SubcutaneousIntramuscular
Research Notes

DAC (Drug Affinity Complex) extends half-life to 6–8 days via albumin binding, creating sustained GH elevation (GH bleed) rather than discrete pulses. This blunted pulsatility is a key mechanistic distinction from No-DAC. Some protocols use 500 mcg twice weekly.

Sequence Motif Viewer

29 Residues
TETRASUBSTITUTEDGRF(1-29)+DAC
BasicAcidicPolarNon-PolarAromaticSpecial
CompoundCompoundTargetReceptor / TargetIt attaches to a lar...Downstream PathwayResearch EffectStudied Effect

Compare CJC-1295 With DAC

CJC-1295 With DAC Frequently Asked Questions

What Is CJC-1295 With DAC?

A long-acting growth-hormone-releasing peptide; banned in sport.

How Does CJC-1295 With DAC Work?

It attaches to a larger protein in your blood (albumin), which stops your body from destroying it quickly. This allows it to constantly knock on the pituitary gland's door to release growth hormone for days.

What Has CJC-1295 With DAC Been Studied For?

In the referenced literature, CJC-1295 With DAC has been studied for GH pulsatile release research, GH-axis anti-aging, Growth hormone deficiency, Extended GH secretion, Anti-aging / longevity via GH axis, Muscle growth via GH axis, Body composition improvement, Fat reduction via GH, Sleep quality enhancement, IGF-1 elevation research, Recovery and repair via GH axis, Bone density via GH stimulation, Collagen synthesis via GH axis, Metabolic rate increase, Adult GH deficiency models, GH secretagogue research, continuous GH release, muscle growth, fat loss, IGF-1 elevation, recovery. This summarizes research focus only and is not a claim of efficacy.

What Is The Reported Half-Life Of CJC-1295 With DAC?

CJC-1295 With DAC has a reported half-life of ~6-8 days (albumin-bound, DAC) in the referenced literature.

Is CJC-1295 With DAC Approved For Human Use?

No. CJC-1295 With DAC is supplied strictly for in vitro laboratory research use only. It is not intended for human or animal consumption, ingestion, or injection, and it has not been evaluated by the FDA.

Regional Research Availability

Pep Nation Lab supplies research-grade CJC-1295 With DAC to qualified researchers and scientific institutions nationwide. Browse verified availability and per-region documentation by state:

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