GHRP-2
Also Known As: Pralmorelin, GHRP2, KP-102, Growth Hormone Releasing Peptide 2, GHRP-2 peptide, GH-releasing peptide 2, Hexarelin analog shorter, GH secretagogue peptide 2, D-Ala-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2, Pralmorelin dihydrochloride, KP102, GHRP 2
GHRP-2 is a research-grade Synthetic hexapeptide GH secretagogue targeting GHS-R1a studied in Muscle Growth & Performance research. It is supplied strictly for in vitro laboratory research use only - not for human or animal consumption, and not FDA-approved.
Evidence Tier: Investigational - In active human clinical trials; not yet approved.
A growth-hormone-releasing peptide used diagnostically in Japan; banned in sport.
At A Glance
| Category | Muscle Growth & Performance |
|---|---|
| Compound Class | Synthetic hexapeptide GH secretagogue (GHRP); ghrelin mimetic |
| Molecular Target | GHS-R1a (ghrelin receptor) agonist on pituitary somatotrophs and hypothalamus; stimulates GH and ghrelin |
| Molecular Weight | 817.99 Da |
| Amino Acid Sequence | D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 |
| CAS Number | 158861-67-7 |
| Half-Life | ~30 minutes |
| WADA Status | prohibited |
| Evidence Tier | Investigational |
Mechanism Of Action
It mimics the hunger hormone (ghrelin) and binds directly to a receptor in the brain, forcing a rapid and intense release of growth hormone into the bloodstream.
Studied For
- GH deficiency diagnosis
- GH secretagogue research
- Growth hormone stimulation
- IGF-1 elevation
- Pituitary function testing
- Anti-aging via GH axis
- Body composition / lean mass
- Fat loss research
- Appetite stimulation
- Muscle growth and repair
- Bone density via GH
- Recovery acceleration
- Ghrelin axis research
- GH pulse amplitude
- Adult GH deficiency models
- Metabolic rate improvement
- Sleep quality via GH
- Cardiac function research
- growth hormone secretagogue
- appetite stimulation
- muscle growth
- recovery
- anti-aging
Reported Research Findings
Validated as a GH-deficiency diagnostic in Japan with potent dose-dependent growth-hormone release in humans.
Safety And Handling Notes
Elevated ACTH, cortisol, and prolactin (more than ipamorelin), transient flushing, increased appetite, water retention.
Approved only as a diagnostic in Japan; not FDA-approved. WADA-prohibited. Research use only in the US.
Regulatory Status
Japan diagnostic; not FDA-approved; WADA S2.
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