GHRP-2 vs GHRP-6: Research Comparison
A Side-By-Side Research Comparison Of GHRP-2 And GHRP-6 - the two first-generation growth-hormone releasing peptides. This Reference Compares Mechanism, Evidence Tier, Molecular Identity, And Pharmacokinetics For Qualified Researchers. For In Vitro Laboratory Research Use Only. Not Medical Advice Or Dosing Guidance.
Side-By-Side Comparison
| GHRP-2 | GHRP-6 | |
|---|---|---|
| Category | Muscle Growth & Performance | Muscle Growth & Performance |
| Compound Class | Synthetic hexapeptide GH secretagogue (GHRP); ghrelin mimetic | Synthetic hexapeptide GH secretagogue (GHRP); first-generation ghrelin mimetic |
| Evidence Tier | Investigational | Research Compound |
| Molecular Target | GHS-R1a (ghrelin receptor) agonist on pituitary somatotrophs and hypothalamus; stimulates GH and ghrelin | GHS-R1a (ghrelin receptor) agonist; stimulates pituitary GH release and endogenous ghrelin; strong appetite/hunger signal |
| Molecular Weight | 817.99 Da | 873.01 Da |
| Amino Acid Sequence | D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 | His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 |
| CAS Number | 158861-67-7 | 87616-84-0 |
| Half-Life | ~30 minutes | ~2.5 hours |
| Studied For | GH deficiency diagnosis, GH secretagogue research, Growth hormone stimulation, IGF-1 elevation | GH release stimulation, Appetite stimulation / hunger research, GI motility research, GH secretagogue research |
About GHRP-2
A growth-hormone-releasing peptide used diagnostically in Japan; banned in sport.
Read The Full GHRP-2 MonographAbout GHRP-6
The original growth-hormone-releasing peptide; strong appetite effect; banned in sport.
Read The Full GHRP-6 MonographKey Differences
- Evidence tier differs: GHRP-2 is classified as Investigational; GHRP-6 is classified as Research Compound.
- Reported half-life differs: GHRP-2 at ~30 minutes versus GHRP-6 at ~2.5 hours.
- Primary molecular target differs: GHRP-2 acts on GHS-R1a (ghrelin receptor) agonist on pituitary somatotrophs and hypothalamus; stimulates GH and ghrelin; GHRP-6 acts on GHS-R1a (ghrelin receptor) agonist; stimulates pituitary GH release and endogenous ghrelin; strong appetite/hunger signal.
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This Comparison Is Provided For In Vitro Laboratory Research Use Only. Not For Human Consumption, Diagnosis, Or Treatment. See The Full Research Disclaimer.