CJC-1295 With DAC vs CJC-1295 Without DAC: Research Comparison

A Side-By-Side Research Comparison Of CJC-1295 With DAC And CJC-1295 Without DAC - the DAC versus non-DAC forms of the CJC-1295 GHRH analog. This Reference Compares Mechanism, Evidence Tier, Molecular Identity, And Pharmacokinetics For Qualified Researchers. For In Vitro Laboratory Research Use Only. Not Medical Advice Or Dosing Guidance.

Side-By-Side Comparison

CJC-1295 With DAC versus CJC-1295 Without DAC research comparison
CJC-1295 With DACCJC-1295 Without DAC
CategoryMuscle Growth & PerformanceMuscle Growth & Performance
Compound ClassLong-acting synthetic GHRH analog with Drug Affinity Complex (DAC) albumin-binding moietyShort-acting synthetic GHRH analog (Mod GRF 1-29); no albumin-binding DAC moiety
Evidence TierResearch CompoundResearch Compound
Molecular TargetGHRH receptor (GHRHR) on pituitary somatotrophs; sustained GH and IGF-1 elevationGHRH receptor (GHRHR) on anterior pituitary somatotrophs; augments natural pulsatile GH release
Molecular Weight3647.1 Da3357.9 Da
Amino Acid Sequencetetrasubstituted GRF(1-29) + DACtetrasubstituted GRF(1-29) amide
CAS Number446262-90-4863288-34-0
Half-Life~6-8 days (albumin-bound, DAC)~30 min (pulsatile)
Studied ForGH pulsatile release research, GH-axis anti-aging, Growth hormone deficiency, Extended GH secretionPulsatile GH simulation, GH secretagogue research, Sleep quality improvement, Stacked with ipamorelin for synergistic GH release
Open CJC-1295 With DAC And CJC-1295 Without DAC In The Interactive Comparison Tool

About CJC-1295 With DAC

A long-acting growth-hormone-releasing peptide; banned in sport.

Read The Full CJC-1295 With DAC Monograph

About CJC-1295 Without DAC

A short-acting growth-hormone-releasing peptide, usually paired with a GHRP; banned in sport.

Read The Full CJC-1295 Without DAC Monograph

Key Differences

  • Reported half-life differs: CJC-1295 With DAC at ~6-8 days (albumin-bound, DAC) versus CJC-1295 Without DAC at ~30 min (pulsatile).
  • Primary molecular target differs: CJC-1295 With DAC acts on GHRH receptor (GHRHR) on pituitary somatotrophs; sustained GH and IGF-1 elevation; CJC-1295 Without DAC acts on GHRH receptor (GHRHR) on anterior pituitary somatotrophs; augments natural pulsatile GH release.

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CJC-1295 With DAC · CJC-1295 Without DAC · Compare Tool · Research Library

This Comparison Is Provided For In Vitro Laboratory Research Use Only. Not For Human Consumption, Diagnosis, Or Treatment. See The Full Research Disclaimer.