BPC-157

Also Known As: Body Protection Compound 157, BPC157, BPC 157, BPC-157, Pentadecapeptide BPC 157, Stable Gastric Pentadecapeptide, BPC 157 Acetate, Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, Bepecin, PLD-116, PL 14736, PL-10, Cytoprotective Peptide, Gastric Pentadecapeptide, Wolverine Peptide

BPC-157 is a research-grade Synthetic pentadecapeptide derived from human gastric juice protein BPC targeting NO-synthase studied in Healing & Recovery research. It is supplied strictly for in vitro laboratory research use only - not for human or animal consumption, and not FDA-approved.

Evidence Tier: Research Compound - No approved human use; sold for laboratory research only.

A popular research healing peptide with strong rodent data but very limited human evidence.

At A Glance

BPC-157 Key Research Facts
CategoryHealing & Recovery
Compound ClassSynthetic pentadecapeptide derived from human gastric juice protein BPC
Molecular TargetNO-synthase, VEGF, FAK/paxillin, EGF receptor, growth hormone receptor; promotes angiogenesis, collagen synthesis, and cytoprotection
Molecular Weight1419.5 Da
Amino Acid SequenceGly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
CAS Number137525-51-0
Half-Life~30 minutes
WADA Statusprohibited
Evidence TierResearch Compound

Mechanism Of Action

It tells your body to build new, healthy blood vessels around the damaged area. More blood means more nutrients, which forces the broken tissue to heal faster.

Studied For

  • GI mucosal healing
  • Tendon / ligament repair
  • Nerve repair
  • Anti-inflammatory
  • Gut health and integrity
  • Leaky gut research
  • IBD / Crohn's disease models
  • Ulcerative colitis models
  • Gastric ulcer healing
  • Intestinal anastomosis healing
  • Wound healing acceleration
  • Muscle tear recovery
  • Sports injury recovery
  • Joint inflammation reduction
  • Bone healing
  • Cartilage repair
  • Neurological recovery
  • Spinal cord injury models
  • Peripheral nerve regeneration
  • Angiogenesis promotion
  • Blood pressure regulation
  • Nitric oxide pathway
  • Growth hormone receptor upregulation
  • Cytoprotection
  • Systemic healing
  • NSAID-induced gastric damage reversal
  • Alcohol-induced gut damage reversal
  • Post-surgical healing
  • Scar reduction
  • Anti-ulcer research
  • joint healing
  • gut healing
  • tendon repair
  • ulcer repair
  • ligament healing
  • muscle tear recovery
  • leaky gut
  • inflammation reduction
  • pain relief
  • soft tissue repair

Reported Research Findings

Evidence is overwhelmingly rodent and in vitro: accelerated healing, angiogenesis, and protection against NSAID gastrointestinal damage. Human evidence is very limited; injectable musculoskeletal claims are not established in humans.

Safety And Handling Notes

Rodent toxicology is benign but human adverse-event data are essentially absent. FDA flags immunogenicity, unknown long-term effects, and a theoretical pro-angiogenic tumor-vascularization risk.

Not approved; flagged by the FDA under its 503A bulk-substances compounding-safety review. Named by example under WADA 2026 S0, so it is prohibited at all times in sport. The pro-angiogenic mechanism is a theoretical concern in any malignancy. Research use only.

Regulatory Status

Not FDA-approved; under FDA compounding-safety review (503A bulk-substances evaluation); research chemical. Named by example on the WADA 2026 Prohibited List under S0 (non-approved substances); prohibited at all times as a Specified substance.

Full Reference Detail

Related Research Guides

Maintained By The Pep Nation Lab Research Team. See Our Editorial Standards And Research Methodology For How This Reference Is Sourced And Reviewed.

This Reference Is Provided For In Vitro Laboratory Research Use Only. Not For Human Consumption. See The Full Research Disclaimer.

References And Citations

  1. PubMed / NCBI Reference
Spec Sheet

BPC-157

Also Known As: Body Protection Compound 157, BPC157, BPC 157, BPC-157, Pentadecapeptide BPC 157, Stable Gastric Pentadecapeptide, BPC 157 Acetate, Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, Bepecin, PLD-116, PL 14736, PL-10, Cytoprotective Peptide, Gastric Pentadecapeptide, Wolverine Peptide

Research CompoundHealing & RecoveryPro-Angiogenic

Explain Like I'm 5

  • Think of BPC-157 as the ultimate "Fix-It" mechanic for your body. Whether it is a torn muscle, a sore joint, or a damaged stomach, it rushes to the site and speeds up the healing process incredibly fast.

A popular research healing peptide with strong rodent data but very limited human evidence.

Identity & Classification
BPC-157 Key Research Facts
ClassSynthetic pentadecapeptide derived from human gastric juice protein BPC
Molecular TargetNO-synthase, VEGF, FAK/paxillin, EGF receptor, growth hormone receptor; promotes angiogenesis, collagen synthesis, and cytoprotection
CategoryHealing & Recovery
Molecular Weight1419.5 Da
Amino Acid SequenceGly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
CAS Number137525-51-0
Parent CompoundGastric juice BPC protein fragment
Classification Flags
Pro-Angiogenic - Promotes New Vessel Growth
Research Metrics at a Glance
229
PubMed Citations
2
Clinical Trials
2 Active

Sequence

15 Residues· 1419.5 Da
GEPPPGKPADDAGLV
Polar / OtherAcidicHydrophobicBasic

Related Compounds

Research Use Only. Not For Human Or Veterinary Use. Information Provided For Laboratory Research Purposes Only.

Research Reference Only — Not Medical Advice. For In Vitro Laboratory Use Only.
Typical Dose250–500 mcg
FrequencyOnce or twice daily
Cycle On4–12 weeks
Cycle Off4 weeks (equal to or half of on-cycle)
Route(s)
SubcutaneousIntramuscularOral (systemic effect reduced)
Research Notes

Most research protocols split the daily dose into AM/PM injections near the site of injury. Oral administration studied for gut-related research at higher doses (1–10 mcg/kg in rodent models). Stable in solution for up to 7 days at 4°C.

Sequence Motif Viewer

59 Residues
GLY-GLU-PRO-PRO-PRO-GLY-LYS-PRO-ALA-ASP-ASP-ALA-GLY-LEU-VAL
BasicAcidicPolarNon-PolarAromaticSpecial
CompoundCompoundTargetReceptor / TargetIt tells your body t...Downstream PathwayResearch EffectStudied Effect

Compare BPC-157

BPC-157 Frequently Asked Questions

What Is BPC-157?

A popular research healing peptide with strong rodent data but very limited human evidence.

How Does BPC-157 Work?

It tells your body to build new, healthy blood vessels around the damaged area. More blood means more nutrients, which forces the broken tissue to heal faster.

What Has BPC-157 Been Studied For?

In the referenced literature, BPC-157 has been studied for GI mucosal healing, Tendon / ligament repair, Nerve repair, Anti-inflammatory, Gut health and integrity, Leaky gut research, IBD / Crohn's disease models, Ulcerative colitis models, Gastric ulcer healing, Intestinal anastomosis healing, Wound healing acceleration, Muscle tear recovery, Sports injury recovery, Joint inflammation reduction, Bone healing, Cartilage repair, Neurological recovery, Spinal cord injury models, Peripheral nerve regeneration, Angiogenesis promotion, Blood pressure regulation, Nitric oxide pathway, Growth hormone receptor upregulation, Cytoprotection, Systemic healing, NSAID-induced gastric damage reversal, Alcohol-induced gut damage reversal, Post-surgical healing, Scar reduction, Anti-ulcer research, joint healing, gut healing, tendon repair, ulcer repair, ligament healing, muscle tear recovery, leaky gut, inflammation reduction, pain relief, soft tissue repair. This summarizes research focus only and is not a claim of efficacy.

What Is The Reported Half-Life Of BPC-157?

BPC-157 has a reported half-life of ~30 minutes in the referenced literature.

Is BPC-157 Approved For Human Use?

No. BPC-157 is supplied strictly for in vitro laboratory research use only. It is not intended for human or animal consumption, ingestion, or injection, and it has not been evaluated by the FDA.

Regional Research Availability

Pep Nation Lab supplies research-grade BPC-157 to qualified researchers and scientific institutions nationwide. Browse verified availability and per-region documentation by state:

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