Oxytocin

Also Known As: Pitocin, Syntocinon, Oxytocin Acetate, Oxytocin hormone, Love hormone, Bonding hormone, Trust hormone, Neuropeptide oxytocin, Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, OXT, Uterocon, Intranasal oxytocin, Social bonding peptide, cuddle hormone, pitocin

Oxytocin is a research-grade Endogenous hypothalamic nonapeptide neurohormone targeting Oxytocin receptor studied in Sexual Health & Hormones research. It is supplied strictly for in vitro laboratory research use only - not for human or animal consumption, and not FDA-approved.

Evidence Tier: Approved Drug - FDA and/or EMA approved with robust human trial data.

The approved labor and bonding hormone; intranasal psychiatric use is investigational.

At A Glance

Oxytocin Key Research Facts
CategorySexual Health & Hormones
Compound ClassEndogenous hypothalamic nonapeptide neurohormone; posterior pituitary release
Molecular TargetOxytocin receptor (OXTR); Gq/cAMP signaling; amygdala fear response modulation; uterine smooth muscle contraction
Molecular Weight1007.19 Da
Amino Acid SequenceCys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (disulfide)
CAS Number50-56-6
Half-Life~3-5 minutes
WADA Statusnot_listed
Evidence TierApproved Drug

Mechanism Of Action

It is released in the brain to modulate emotional and social behaviors. It dampens the fear response in the amygdala, reducing anxiety and promoting feelings of trust and pair bonding.

Studied For

  • Labor induction / postpartum hemorrhage
  • Milk let-down / lactation
  • Social cognition research (intranasal)
  • Autism spectrum disorder research
  • Anxiety and stress reduction research
  • Trust and social bonding research
  • Erectile dysfunction research
  • Female sexual dysfunction research
  • PTSD / trauma research
  • Addiction research
  • Eating disorder research
  • Pair bonding / monogamy research
  • Depression models
  • Schizophrenia research
  • Wound healing via oxytocin receptors
  • Uterine contraction induction
  • Male sexual arousal research
  • bonding
  • social anxiety
  • autism research
  • stress reduction
  • libido
  • wound healing

Reported Research Findings

Established uterotonic and milk-ejection use. Intranasal psychiatric trials for autism and social cognition are mixed and often fail to replicate.

Safety And Handling Notes

Obstetric IV use can cause uterine hyperstimulation, water intoxication, and blood-pressure changes; intranasal use is mild.

Obstetric contraindications apply; water-intoxication risk with high doses and hypotonic fluids; intranasal psychiatric use is unapproved.

Regulatory Status

FDA/EMA-approved Rx (injectable); not WADA-prohibited.

Full Reference Detail

Related Research Guides

Maintained By The Pep Nation Lab Research Team. See Our Editorial Standards And Research Methodology For How This Reference Is Sourced And Reviewed.

This Reference Is Provided For In Vitro Laboratory Research Use Only. Not For Human Consumption. See The Full Research Disclaimer.

References And Citations

  1. go.drugbank.com
  2. PubMed / NCBI Reference
Spec Sheet

Oxytocin

Also Known As: Pitocin, Syntocinon, Oxytocin Acetate, Oxytocin hormone, Love hormone, Bonding hormone, Trust hormone, Neuropeptide oxytocin, Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, OXT, Uterocon, Intranasal oxytocin, Social bonding peptide, cuddle hormone, pitocin

Approved DrugSexual Health & Hormones

Explain Like I'm 5

  • Oxytocin is the "hug hormone." It is the natural chemical that makes you feel bonded, trusting, and deeply connected to your loved ones, while also lowering stress and anxiety.

The approved labor and bonding hormone; intranasal psychiatric use is investigational.

Identity & Classification
Oxytocin Key Research Facts
ClassEndogenous hypothalamic nonapeptide neurohormone; posterior pituitary release
Molecular TargetOxytocin receptor (OXTR); Gq/cAMP signaling; amygdala fear response modulation; uterine smooth muscle contraction
CategorySexual Health & Hormones
Molecular Weight1007.19 Da
Amino Acid SequenceCys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (disulfide)
CAS Number50-56-6
Parent CompoundPosterior pituitary hormone
Research Metrics at a Glance
33,578
PubMed Citations
553
Clinical Trials
553 Active

Related Compounds

Research Use Only. Not For Human Or Veterinary Use. Information Provided For Laboratory Research Purposes Only.

Research Reference Only — Not Medical Advice. For In Vitro Laboratory Use Only.
Typical Dose10–40 IU (intranasal)
FrequencyOnce daily or as-needed (behavioral research)
Cycle On4 weeks
Cycle Off2–4 weeks
Route(s)
IntranasalSubcutaneousIntravenous
Research Notes

Social bonding and anxiolytic research. Intranasal is primary route for CNS research (10–40 IU per session). IV used in labor research (highly dose-dependent). Subcutaneous used in some metabolic/pain research. Avoid chronic high-dose use — receptor desensitization observed.

Sequence Motif Viewer

50 Residues
CYS-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2(DISULFIDE)
BasicAcidicPolarNon-PolarAromaticSpecial
CompoundCompoundTargetReceptor / TargetIt is released in th...Downstream PathwayResearch EffectStudied Effect

Compare Oxytocin

Oxytocin Frequently Asked Questions

What Is Oxytocin?

The approved labor and bonding hormone; intranasal psychiatric use is investigational.

How Does Oxytocin Work?

It is released in the brain to modulate emotional and social behaviors. It dampens the fear response in the amygdala, reducing anxiety and promoting feelings of trust and pair bonding.

What Has Oxytocin Been Studied For?

In the referenced literature, Oxytocin has been studied for Labor induction / postpartum hemorrhage, Milk let-down / lactation, Social cognition research (intranasal), Autism spectrum disorder research, Anxiety and stress reduction research, Trust and social bonding research, Erectile dysfunction research, Female sexual dysfunction research, PTSD / trauma research, Addiction research, Eating disorder research, Pair bonding / monogamy research, Depression models, Schizophrenia research, Wound healing via oxytocin receptors, Uterine contraction induction, Male sexual arousal research, bonding, social anxiety, autism research, stress reduction, libido, wound healing. This summarizes research focus only and is not a claim of efficacy.

What Is The Reported Half-Life Of Oxytocin?

Oxytocin has a reported half-life of ~3-5 minutes in the referenced literature.

Is Oxytocin Approved For Human Use?

No. Oxytocin is supplied strictly for in vitro laboratory research use only. It is not intended for human or animal consumption, ingestion, or injection, and it has not been evaluated by the FDA.

Regional Research Availability

Pep Nation Lab supplies research-grade Oxytocin to qualified researchers and scientific institutions nationwide. Browse verified availability and per-region documentation by state:

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