HCG
Also Known As: Human Chorionic Gonadotropin, Choriogonadotropin alfa, hCG, HCG hormone, Pregnyl, Novarel, Profasi, Ovidrel, Choragon, Choriomon, Luteinizing hormone analog, LH analog, hCG injection, Gonadotropin fertility drug, Testosterone support peptide, hCG for TRT, pregnyl
HCG is a research-grade Glycoprotein gonadotropin hormone targeting LH/hCG receptor studied in Sexual Health & Hormones research. It is supplied strictly for in vitro laboratory research use only - not for human or animal consumption, and not FDA-approved.
Evidence Tier: Approved Drug - FDA and/or EMA approved with robust human trial data.
An approved fertility and testosterone-support hormone; prohibited in males in sport.
At A Glance
| Category | Sexual Health & Hormones |
|---|---|
| Compound Class | Glycoprotein gonadotropin hormone (recombinant/extracted); LH analog |
| Molecular Target | LH/hCG receptor (LHCGR) on Leydig cells (testes) and granulosa/luteal cells (ovary); stimulates testosterone and progesterone synthesis |
| Molecular Weight | 36700 Da |
| Amino Acid Sequence | alpha/beta heterodimer glycoprotein |
| CAS Number | 9002-61-3 |
| Half-Life | ~24-36 hours |
| WADA Status | prohibited_males |
| Evidence Tier | Approved Drug |
Mechanism Of Action
It perfectly mimics a natural messenger hormone (LH). When it hits the reproductive organs, it tricks them into staying active and producing testosterone and sperm naturally.
Studied For
- Male hypogonadism
- Fertility treatment
- TRT support / testicular maintenance
- Ovulation induction (women)
- Testosterone production stimulation
- Spermatogenesis support
- Cryptorchidism (undescended testes)
- Luteal phase support
- IVF / ART ovulation trigger
- LH substitute therapy
- Testicular atrophy prevention on TRT
- Leydig cell stimulation
- Delayed puberty research
- Pituitary LH deficiency models
- Testosterone deficiency without LH elevation
- testosterone production
- fertility
- PCT
- post cycle therapy
- weight loss
- cryptorchidism
Reported Research Findings
Established human use for ovulation triggering and for restoring testosterone and spermatogenesis. The hCG diet weight-loss claim is not supported.
Safety And Handling Notes
Ovarian hyperstimulation syndrome, multiple gestation, injection-site reactions, gynecomastia and edema in men.
Contraindicated in hormone-dependent tumors and precocious puberty. WADA-prohibited in males because it raises endogenous testosterone.
Regulatory Status
FDA/EMA-approved Rx; WADA-prohibited in males.
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This Reference Is Provided For In Vitro Laboratory Research Use Only. Not For Human Consumption. See The Full Research Disclaimer.