Technical Data Sheet
HCG
Also Known As: Human Chorionic Gonadotropin, Choriogonadotropin alfa, hCG, HCG hormone, Pregnyl, Novarel, Profasi, Ovidrel, Choragon, Choriomon, Luteinizing hormone analog, LH analog, hCG injection, Gonadotropin fertility drug, Testosterone support peptide, hCG for TRT, pregnyl
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| Evidence Tier | Approved Drug |
|---|---|
| Category | Sexual Health & Hormones |
| Class | Glycoprotein gonadotropin hormone (recombinant/extracted); LH analog |
| Molecular Target | LH/hCG receptor (LHCGR) on Leydig cells (testes) and granulosa/luteal cells (ovary); stimulates testosterone and progesterone synthesis |
| Sequence | alpha/beta heterodimer glycoprotein |
| Molecular Weight | ~36-40 kDa |
| CAS | 9002-61-3 |
| Parent | Placental gonadotropin |
| Mechanism | It perfectly mimics a natural messenger hormone (LH). When it hits the reproductive organs, it tricks them into staying active and producing testosterone and sperm naturally. |
| Studied For | Male hypogonadism, Fertility treatment, TRT support / testicular maintenance, Ovulation induction (women), Testosterone production stimulation, Spermatogenesis support, Cryptorchidism (undescended testes), Luteal phase support, IVF / ART ovulation trigger, LH substitute therapy, Testicular atrophy prevention on TRT, Leydig cell stimulation, Delayed puberty research, Pituitary LH deficiency models, Testosterone deficiency without LH elevation, testosterone production, fertility, PCT, post cycle therapy, weight loss, cryptorchidism |
| Administration Route | Injection Only |
| Form | lyophilized + diluent |
| Diluent | supplied diluent; gentle, no vigorous shaking |
| Storage Temperature | refrigerate after reconstitution |
| Light Sensitive | Yes |
| Freeze / Thaw | avoid |
| Reconstituted Shelf Life | 30 Days |
| Handling Notes | Interferes with hCG-based assays. |
| Regulatory | FDA/EMA-approved Rx; WADA-prohibited in males. |
| Sources |