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| Attribute | ||
|---|---|---|
Research Summary | Selank acts like a calming blanket for a stressed-out brain. It completely wipes away anxiety, stops racing thoughts, and helps you focus clearly without making you feel sleepy or tired. | DSIP stands for Delta Sleep-Inducing Peptide. It acts like a natural lullaby for your brain, helping you fall into the deepest, most restful stage of sleep without feeling groggy the next morning. |
Studied For | Generalized anxiety disorder researchStress modulationCognition / attention / focusMemory enhancementAnxiety reduction without sedationBDNF upregulationSerotonin system modulationDopamine modulationGABAergic modulationImmune modulation via tuftsin analogAntidepressant researchAlcohol withdrawal researchADHD researchNootropic researchNeuroplasticityAdaptive stress responsestress reliefcognitive enhancementfocusanxiety reductiondepressionimmune modulationBDNF increase | Sleep researchDelta-wave sleep promotionSleep onset latency reductionInsomnia researchStress modulationHPA axis regulationHypothalamic regulationCortisol regulationPain modulationOpiate withdrawal researchCircadian rhythm supportAntioxidant neuroprotectionNeuropeptide signaling researchLH/GH sleep pulsatilityREM sleep researchSleep architecture optimizationdeep sleepinsomniastress reductionsleep qualitypain reliefLH regulation |
Research Areas | CognitiveImmuneSleep & Circadian | Sleep & CircadianCognitiveImmuneLongevity |
Best Stacked With | semaxdsippinealonbac-water | melatoninselankpinealonbac-water |
Overview | ||
Category | Immunity & Wellness | Immunity & Wellness |
Compound Class | Synthetic heptapeptide anxiolytic / nootropic; tuftsin analog (Thr-Lys-Pro-Arg-Pro-Gly-Pro) | Endogenous neuropeptide (9 amino acids) produced in hypothalamus |
Molecular Target | Enkephalinase inhibition; GABA-A receptor modulation; BDNF upregulation; serotonin/dopamine pathway; T-cell tuftsin receptor | Hypothalamic receptors; modulates GH, LH, corticosteroid release; delta-wave EEG promotion |
Aliases / AKA | TP-7Selank peptideThr-Lys-Pro-Arg-Pro-Gly-Pro tuftsin analogAnxiolytic peptideRussian anti-anxiety peptideTuftsin analog | Delta Sleep-Inducing PeptideDSIP peptideDelta sleep peptideDSIP neuropeptideTrp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-GluSleep peptide |
Parent Compound | Tuftsin analog | Endogenous neuropeptide |
Molecular Weight | 751.88 Da | 848.8 Da |
Amino Acid Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
CAS Number | 129954-34-3 | 62568-57-4 |
Year Discovered | Not Listed | Not Listed |
Pro-Angiogenic | No | No |
GLP-1 Class | No | No |
Purity | Not Listed | Not Listed |
Identity | ||
Evidence Tier | ||
Risk Level | ||
PubMed Citations | 202 Good | 545 Good |
Clinical Trials | 22 Active | 4444 Active |
Regulatory Status | Registered in Russia; not FDA or EMA approved. | Not approved anywhere; research chemical. |
Evidence & Regulatory | ||
Half-Life | ~2 minutes | ~15 minutes |
Typical Frequency | Not Listed | Not Listed |
Administration Route | Injection Only | Injection Only |
Mechanism / PK | Not Listed | Not Listed |
Reported Findings | Russian studies report anxiolytic efficacy without sedation, dependence, or withdrawal. Largely single-lineage and preliminary; no large Western trials. | Animal studies report EEG delta induction and anti-stress effects. Human data are limited, dated, and inconsistently reproduced. Weak. |
Side Effects Noted | Reported well tolerated; intranasal use may cause local nasal irritation. | Sparse safety data; reportedly low toxicity in early work; poorly characterized. |
Warnings | Narrow, non-replicated evidence; registered as a medicine in Russia but not FDA or EMA approved. Research use only elsewhere. | Unconfirmed mechanism and no robust modern trials; rapidly degraded. Research use only. |
Pharmacology | ||
Form | lyophilized | lyophilized |
Diluent | bacteriostatic water | bacteriostatic or sterile water |
Storage Temp | frozen, dark | frozen, dark |
Light Sensitive | Yes | Yes |
Freeze / Thaw | avoid | avoid |
Handling Notes | Often studied as an intranasal formulation. | Very low metabolic stability; in-vitro half-life around 15 minutes. |
Reconstituted Shelf Life | 28 Days Refrigerated | 14 Days Refrigerated |
Handling & Storage | ||
Pep Nation Lab's comparison tool puts research-grade peptides and compounds head to head - mechanism of action, molecular target, evidence tier, molecular weight, sequence, half-life, and documented research focus - so qualified researchers can evaluate the differences that matter. Every data point is drawn from a referenced monograph. For in vitro laboratory research use only.
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Two GHRH analogs studied on the growth-hormone axis.
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An amylin analog versus a GLP-1 agonist in metabolic research.
A mitochondrial-derived peptide versus an HGH fragment in metabolic research.
Melanocortin versus kisspeptin pathways in reproductive research.
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A potent versus a highly selective ghrelin-receptor secretagogue.
Two GHRH analogs with contrasting half-life profiles.
A direct IGF-1 analog versus a growth-hormone secretagogue.
The DAC versus non-DAC forms of the CJC-1295 GHRH analog.
Two Russian-developed nootropic and anxiolytic research peptides.
Two mitochondrial-targeted peptides in cellular-energy research.
Two immune-modulating research peptides with distinct mechanisms.
Two HGH-fragment analogs studied for fat-metabolism research.
Next-generation multi-receptor incretin agonists in metabolic research.
Two leading tissue-repair peptides with distinct healing mechanisms.
A systemic repair peptide versus a copper peptide for tissue and skin research.
A GHRH analog versus a selective ghrelin-receptor secretagogue on the GH axis.
A dual incretin agonist versus an amylin analog in metabolic research.
A triple incretin agonist versus an amylin analog in weight research.
Two metabolic research compounds targeting mitochondrial and NNMT pathways.
NAD+ metabolism versus a mitochondrial-derived peptide in longevity research.
Two copper research peptides studied for skin and hair.
A long-acting versus a short-acting GHRH analog.
A selective versus a first-generation ghrelin-receptor secretagogue.
A GLP-1 agonist versus a GLP-1/amylin combination in metabolic research.
Two peptides studied for gut and mucosal repair.
Melanocortin versus oxytocin pathways in intimacy and libido research.
Two thymic immune-modulating research peptides.
An anxiolytic nootropic versus a sleep-associated research peptide.
Direct IGF-1 signaling versus myostatin inhibition in muscle research.
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Browse the full research catalog or the A To Z index to compare any compound.
Any research-grade compound in the library can be placed side by side - up to four at a time. The tool compares mechanism of action, molecular target, evidence tier, molecular weight, amino acid sequence, reported half-life, and what each compound has been studied for, all drawn from referenced monographs.
The evidence tier reflects how extensively a compound has been studied in the referenced literature, from early preclinical signals through to compounds with human clinical data. It is a research-quality signal only, never a safety or efficacy endorsement.
Each comparison page is generated from the same referenced compound database - a genuine side-by-side of mechanism, identity, pharmacokinetics, and evidence, plus data-derived key differences. They are curated, not auto-generated thin pages.
No. Every comparison is for in vitro laboratory research use only. Nothing here is medical advice, a treatment recommendation, or dosing guidance, and no product is for human or animal consumption.
