What Can I Compare With The Pep Nation Lab Comparison Tool?

Any research-grade compound in the library can be placed side by side - up to four at a time. The tool compares mechanism of action, molecular target, evidence tier, molecular weight, amino acid sequence, reported half-life, and what each compound has been studied for, all drawn from referenced monographs.

What Does The Evidence Tier Mean?

The evidence tier reflects how extensively a compound has been studied in the referenced literature, from early preclinical signals through to compounds with human clinical data. It is a research-quality signal only, never a safety or efficacy endorsement.

How Are "X vs Y" Comparison Pages Built?

Each comparison page is generated from the same referenced compound database - a genuine side-by-side of mechanism, identity, pharmacokinetics, and evidence, plus data-derived key differences. They are curated, not auto-generated thin pages.

Is Any Of This Medical Or Dosing Advice?

No. Every comparison is for in vitro laboratory research use only. Nothing here is medical advice, a treatment recommendation, or dosing guidance, and no product is for human or animal consumption.

Compare Compounds

Select Up To Four Compounds To Review Their Evidence, Targets, And Handling Side By Side.
For Laboratory Research Only

2/4

Diff ModeHide Identical

PinealonB-80

EpithalonB+91

Top Pick: EpithalonTap to see full verdict & analysis

Pinealon

0/100

Grade B-

Leads in safety profile

Evidence

Safety

Science

Coverage

Handling

Depth

Epithalon

0/100

Grade B+

Leads in safety profile

Evidence

Safety

Science

Coverage

Handling

Depth

Unique: Immune

Research Profile Radar - hover axes for details

Pinealon

Epithalon

Zoom100%

Attribute	Pinealon B-	Epithalon B+
Research Summary	Pinealon is a tiny brain-protector. It dives deep into your brain cells and shields them from stress, toxins, and aging, helping you maintain a sharp memory and a calm mind.	Epithalon is an anti-aging master switch. Imagine your cells have little shoelace caps on their DNA that wear down as you get older. Epithalon rebuilds those caps, making old cells act young again.
Studied For	NeuroprotectionNeuronal agingCognition / memory researchRetinal cell neuroprotectionIschemia-induced brain damage modelsParkinson's researchAge-related cognitive declineSleep regulation via pinealCircadian rhythm supportDNA oxidative damage protectionBrain antioxidant researchGlaucoma / ocular neurodegeneration researchLongevity via neuroprotectionStress-induced neurotoxicity modelsbrain healthcircadian rhythmcognitive functionmemoryanti-agingneurological repair	Telomere elongationAnti-aging / longevityCircadian rhythm regulationAntioxidant defenseMelatonin production stimulationPineal gland restorationImmune system enhancement in agingLifespan extension modelsCancer prevention researchDNA repairNeuroendocrine system regulationOxidative stress reductionAge-related disease preventionSleep quality via melatoninSkin anti-agingRetinal cell protectionInflammatory cytokine modulationlongevityanti-agingsleep regulationlife extensioncircadian rhythmmelatonin productiontelomere lengtheningantioxidant
Research Areas	LongevityCognitiveSleep & Circadian	LongevityImmuneSleep & CircadianCognitive
Best Stacked With	epithalonsemaxselankmelatoninbac-water	nad-plusss-31thymalinpinealonmelatoninbac-water
Overview
Category	Anti-Aging & Longevity	Anti-Aging & Longevity
Compound Class	Synthetic tripeptide bioregulator (Glu-Asp-Arg) derived from pineal gland peptide complex	Synthetic tetrapeptide bioregulator derived from pineal gland epithalamin
Molecular Target	Epigenetic regulation of neuronal genes; antioxidant enzyme induction; serotonin/melatonin pathway modulation	Telomerase activation (TERT); pineal melatonin synthesis; antioxidant enzyme upregulation
Aliases / AKA	EDRGlu-Asp-ArgPinealon peptideEDR tripeptideNeuroprotective tripeptidePineal bioregulator	EpitalonEpithalaminAla-Glu-Asp-GlyAEDG peptideEpithalon tetrapeptidePineal peptide bioregulator
Parent Compound	Pineal bioregulator lineage	Pineal extract epithalamin fragment
Molecular Weight	418.4 Da	390.35 Da
Amino Acid Sequence	`Glu-Asp-Arg (EDR)`	`Ala-Glu-Asp-Gly (AEDG)`
CAS Number	175175-23-2	307297-39-8
Year Discovered	Not Listed	Not Listed
Pro-Angiogenic	No	No
GLP-1 Class	No	No
Purity	Not Listed	Not Listed
Identity
Evidence Tier
Risk Level
PubMed Citations	1,544 Extensive	217 Good
Clinical Trials	Not Listed	Not Listed
Regulatory Status	Not FDA or EMA approved; research chemical.	Not FDA or EMA approved; research chemical only.
Evidence & Regulatory
Half-Life	~5-10 minutes	~10-15 minutes
Typical Frequency	Not Listed	Not Listed
Administration Route	Injection Only	Injection Only
Mechanism / PK	Not Listed	Not Listed
Reported Findings	In vitro and rodent studies report reduced oxidative stress and neuroprotection. No robust independent human data. Preliminary.	In vitro work in human fibroblasts reported induced telomerase activity and telomere elongation. Animal data show antioxidant and antitumor signals. Human evidence is limited, old, and from a single research group, so it is preliminary.
Side Effects Noted	No characterized human adverse-event profile; reported tolerable in limited preclinical work.	No well characterized adverse-event profile; reported well tolerated in sparse low-quality studies. Theoretical concern that telomerase upregulation could favor proliferation of malignant cells.
Warnings	Not approved; preliminary, single-lineage evidence. Research use only. CAS should be verified against a supplier certificate of analysis.	Not approved anywhere; thin, non-independent human evidence. Research use only.
Pharmacology
Form	lyophilized	lyophilized
Diluent	bacteriostatic or sterile water	bacteriostatic or sterile water
Storage Temp	-20C, dark	-20C frozen long-term, refrigerate after reconstitution
Light Sensitive	Yes	Yes
Freeze / Thaw	avoid	avoid
Handling Notes	Very short half-life.	Very short plasma half-life.
Reconstituted Shelf Life	28 Days Refrigerated	28 Days Refrigerated
Handling & Storage

Popular Research Comparisons

BPC-157 vs TB-500 / Thymosin Beta-4
The two most-studied research peptides for tissue repair and recovery.
Semaglutide vs Tirzepatide
Single GLP-1 versus dual GLP-1/GIP incretin agonists in metabolic research.
Tirzepatide vs Retatrutide
Dual versus triple incretin receptor agonists in weight-research models.
Semaglutide vs Retatrutide
A GLP-1 agonist versus a triple-agonist incretin in metabolic research.
CJC-1295 With DAC vs Ipamorelin
A GHRH analog versus a selective ghrelin-receptor secretagogue.
Ipamorelin vs Sermorelin
A ghrelin-receptor secretagogue versus a GHRH analog for growth-hormone research.
Sermorelin vs Tesamorelin
Two GHRH analogs studied on the growth-hormone axis.
GHRP-2 vs GHRP-6
The two first-generation growth-hormone releasing peptides.
Cagrilintide vs Semaglutide
An amylin analog versus a GLP-1 agonist in metabolic research.
MOTS-c vs AOD9604
A mitochondrial-derived peptide versus an HGH fragment in metabolic research.
PT-141 vs Kisspeptin-10
Melanocortin versus kisspeptin pathways in reproductive research.
Epithalon vs NAD+
A telomerase-pathway peptide versus NAD+ metabolism in longevity research.
Hexarelin vs Ipamorelin
A potent versus a highly selective ghrelin-receptor secretagogue.
CJC-1295 With DAC vs Tesamorelin
Two GHRH analogs with contrasting half-life profiles.
IGF-1 LR3 vs Ipamorelin
A direct IGF-1 analog versus a growth-hormone secretagogue.
CJC-1295 With DAC vs CJC-1295 Without DAC
The DAC versus non-DAC forms of the CJC-1295 GHRH analog.
Selank vs Semax
Two Russian-developed nootropic and anxiolytic research peptides.
SS-31 vs MOTS-c
Two mitochondrial-targeted peptides in cellular-energy research.
Thymosin Alpha-1 vs LL-37
Two immune-modulating research peptides with distinct mechanisms.
AOD9604 vs HGH Fragment 176-191
Two HGH-fragment analogs studied for fat-metabolism research.
Retatrutide vs Survodutide
Next-generation multi-receptor incretin agonists in metabolic research.
BPC-157 vs GHK-Cu
Two leading tissue-repair peptides with distinct healing mechanisms.
TB-500 / Thymosin Beta-4 vs GHK-Cu
A systemic repair peptide versus a copper peptide for tissue and skin research.
Tesamorelin vs Ipamorelin
A GHRH analog versus a selective ghrelin-receptor secretagogue on the GH axis.
Tirzepatide vs Cagrilintide
A dual incretin agonist versus an amylin analog in metabolic research.
Retatrutide vs Cagrilintide
A triple incretin agonist versus an amylin analog in weight research.
MOTS-c vs 5-Amino-1MQ
Two metabolic research compounds targeting mitochondrial and NNMT pathways.
NAD+ vs MOTS-c
NAD+ metabolism versus a mitochondrial-derived peptide in longevity research.
GHK-Cu vs AHK-Cu
Two copper research peptides studied for skin and hair.
CJC-1295 With DAC vs Sermorelin
A long-acting versus a short-acting GHRH analog.
Ipamorelin vs GHRP-6
A selective versus a first-generation ghrelin-receptor secretagogue.
Semaglutide vs The Appetite Crusher Stack
A GLP-1 agonist versus a GLP-1/amylin combination in metabolic research.
BPC-157 vs KPV
Two peptides studied for gut and mucosal repair.
PT-141 vs Oxytocin
Melanocortin versus oxytocin pathways in intimacy and libido research.
Thymosin Alpha-1 vs Thymalin
Two thymic immune-modulating research peptides.
Selank vs DSIP
An anxiolytic nootropic versus a sleep-associated research peptide.
IGF-1 LR3 vs Follistatin
Direct IGF-1 signaling versus myostatin inhibition in muscle research.
SS-31 vs NAD+
A mitochondrial-targeted peptide versus NAD+ in cellular-energy research.
BPC-157 vs The Wolverine Stack
Single BPC-157 versus the combined BPC-157 and TB-500 blend in recovery research.
Ipamorelin vs The Fountain of Youth Stack
Ipamorelin alone versus the CJC-1295 and ipamorelin blend on the growth-hormone axis.
Semax vs Cerebrolysin
A synthetic ACTH-fragment nootropic versus a neurotrophic peptide preparation in cognitive research.
Melatonin vs DSIP
Two sleep-research compounds with distinct mechanisms.
GHK-Cu vs SNAP-8
A copper tripeptide versus an acetyl hexapeptide in cosmetic and skin research.
FOXO4-DRI vs Epithalon
A senolytic peptide versus a telomerase-pathway peptide in longevity research.
AICAR vs 5-Amino-1MQ
Two metabolic research compounds targeting the AMPK and NNMT pathways.
Tesamorelin vs HGH Fragment 176-191
A GHRH analog versus an HGH fragment in fat-metabolism research.
MOTS-c vs AICAR
Two AMPK-associated mitochondrial and metabolic research compounds.
ARA-290 vs BPC-157
Two peptides studied for tissue protection and repair.
VIP vs KPV
Two peptides studied for immune and inflammatory modulation.
Pinealon vs Epithalon
Two peptide bioregulators studied in longevity and neuro research.
Survodutide vs Tirzepatide
A glucagon/GLP-1 dual agonist versus a GIP/GLP-1 dual agonist in metabolic research.

Accessing Library

Compare Compounds

Compare Research Peptides Side By Side

Popular Research Comparisons

Compounds You Can Compare

Comparison Tool FAQ