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| Attribute | ||
|---|---|---|
Research Summary | Think of BPC-157 as the ultimate "Fix-It" mechanic for your body. Whether it is a torn muscle, a sore joint, or a damaged stomach, it rushes to the site and speeds up the healing process incredibly fast. | This is the ultimate tag-team for healing. BPC-157 builds the roads (blood vessels) to the injury, and TB-500 brings in the heavy construction crew to rebuild the torn muscle or tendon. Together, they heal damage faster than anything else. |
Studied For | GI mucosal healingTendon / ligament repairNerve repairAnti-inflammatoryGut health and integrityLeaky gut researchIBD / Crohn's disease modelsUlcerative colitis modelsGastric ulcer healingIntestinal anastomosis healingWound healing accelerationMuscle tear recoverySports injury recoveryJoint inflammation reductionBone healingCartilage repairNeurological recoverySpinal cord injury modelsPeripheral nerve regenerationAngiogenesis promotionBlood pressure regulationNitric oxide pathwayGrowth hormone receptor upregulationCytoprotectionSystemic healingNSAID-induced gastric damage reversalAlcohol-induced gut damage reversalPost-surgical healingScar reductionAnti-ulcer researchjoint healinggut healingtendon repairulcer repairligament healingmuscle tear recoveryleaky gutinflammation reductionpain reliefsoft tissue repair | Soft-tissue repair researchCombined healing and regenerationTendon repair accelerationLigament healingMuscle injury recoverySports injury researchPost-surgical healingWound closure accelerationJoint repairAnti-inflammatory synergyNerve regeneration with tissue repairComprehensive tissue healing protocolGI healing with systemic repairAthletic recovery researchInjury rehabilitation researchtissue repairjoint healingrecoverymuscle tearinflammationsystemic healing |
Research Areas | Healing & RecoveryTissue RepairGut Health & GI RepairPain & InflammationJoint & Bone SupportImmune | Healing & RecoveryTissue RepairPain & InflammationJoint & Bone Support |
Best Stacked With | tb-500ghk-cukpvll-37bac-water | ghk-cukpvsermorelinipamorelinbac-water |
Overview | ||
Category | Healing & Recovery | Peptide Stacks |
Compound Class | Synthetic pentadecapeptide derived from human gastric juice protein BPC | Peptide stack (BPC-157 + Thymosin Beta-4) |
Molecular Target | NO-synthase, VEGF, FAK/paxillin, EGF receptor, growth hormone receptor; promotes angiogenesis, collagen synthesis, and cytoprotection | Dual-pathway: BPC-157 via NO/VEGF/EGF; TB-500 via actin-G sequestration and VEGF upregulation |
Aliases / AKA | Body Protection Compound 157BPC157BPC 157BPC-157Pentadecapeptide BPC 157Stable Gastric Pentadecapeptide | BPC TB stackBPC+TBBPC TB comboTB BPC stackBPC-157 Thymosin Beta-4 stackBPC TB-500 |
Parent Compound | Gastric juice BPC protein fragment | BPC-157 and TB-500 |
Molecular Weight | 1419.5 Da | combination |
Amino Acid Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val | BPC-157 + Thymosin beta-4 fragment |
CAS Number | 137525-51-0 | n/a |
Year Discovered | Not Listed | Not Listed |
Pro-Angiogenic | Yes - Promotes New Vessel Growth | Yes - Promotes New Vessel Growth |
GLP-1 Class | No | No |
Purity | Not Listed | Not Listed |
Identity | ||
Evidence Tier | ||
Risk Level | ||
PubMed Citations | 224 Good | 8 Sparse |
Clinical Trials | 22 Active | Not Listed |
Regulatory Status | Not FDA-approved; under FDA compounding-safety review (503A bulk-substances evaluation); research chemical. | Not FDA-approved; TB-500 WADA-prohibited. |
Evidence & Regulatory | ||
Half-Life | ~30 minutes | ~30 minutes (BPC-157) / ~30 hours (TB-500) |
Typical Frequency | Not Listed | Not Listed |
Administration Route | Injection Only | Injection Only |
Mechanism / PK | Not Listed | Not Listed |
Reported Findings | Evidence is overwhelmingly rodent and in vitro: accelerated healing, angiogenesis, and protection against NSAID gastrointestinal damage. Human evidence is very limited; injectable musculoskeletal claims are not established in humans. | No controlled human combination-trial evidence exists; both components are preclinical in this context. |
Side Effects Noted | Rodent toxicology is benign but human adverse-event data are essentially absent. FDA flags immunogenicity, unknown long-term effects, and a theoretical pro-angiogenic tumor-vascularization risk. | Inherits both components: limited human safety data and a doubled pro-angiogenic theoretical tumor caveat. |
Warnings | Not approved; flagged by the FDA under its 503A bulk-substances compounding-safety review. The pro-angiogenic mechanism is a theoretical concern in any malignancy. Research use only. | Both components are unapproved; TB-500 is WADA-prohibited and BPC-157 falls under WADA non-approved-substance rules. Research use only. |
Pharmacology | ||
Form | lyophilized | lyophilized |
Diluent | bacteriostatic or sterile water; swirl, do not shake | bacteriostatic or sterile water; swirl |
Storage Temp | 2-8C; -20C long-term, dark | 2-8C; -20C long-term, dark |
Light Sensitive | Yes | Yes |
Freeze / Thaw | avoid | avoid |
Handling Notes | Reported stable in gastric juice; arginate salt aids stability. | See component profiles for detail. |
Reconstituted Shelf Life | 28 Days Refrigerated | 28 Days Refrigerated |
Handling & Storage | ||
Pep Nation Lab's comparison tool puts research-grade peptides and compounds head to head - mechanism of action, molecular target, evidence tier, molecular weight, sequence, half-life, and documented research focus - so qualified researchers can evaluate the differences that matter. Every data point is drawn from a referenced monograph. For in vitro laboratory research use only.
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Any research-grade compound in the library can be placed side by side - up to four at a time. The tool compares mechanism of action, molecular target, evidence tier, molecular weight, amino acid sequence, reported half-life, and what each compound has been studied for, all drawn from referenced monographs.
The evidence tier reflects how extensively a compound has been studied in the referenced literature, from early preclinical signals through to compounds with human clinical data. It is a research-quality signal only, never a safety or efficacy endorsement.
Each comparison page is generated from the same referenced compound database - a genuine side-by-side of mechanism, identity, pharmacokinetics, and evidence, plus data-derived key differences. They are curated, not auto-generated thin pages.
No. Every comparison is for in vitro laboratory research use only. Nothing here is medical advice, a treatment recommendation, or dosing guidance, and no product is for human or animal consumption.