Glutathione
Also Known As: GSH, L-Glutathione, Reduced glutathione, Gamma-glutamylcysteinylglycine, Glutathione reduced, L-GSH, Glutathiol, Tathion, Isethion, Glutatione, Master antioxidant, Endogenous antioxidant tripeptide, GSH peptide, Liver antioxidant, Glu-Cys-Gly, master antioxidant
Glutathione is a research-grade Endogenous tripeptide targeting Reactive oxygen species scavenging studied in Anti-Aging & Longevity research. It is supplied strictly for in vitro laboratory research use only - not for human or animal consumption, and not FDA-approved.
Evidence Tier: Research Compound - No approved human use; sold for laboratory research only.
The body main antioxidant tripeptide, studied for oxidative-stress and liver research; injectable forms are compounded.
At A Glance
| Category | Anti-Aging & Longevity |
|---|---|
| Compound Class | Endogenous tripeptide (Glu-Cys-Gly); master intracellular antioxidant |
| Molecular Target | Reactive oxygen species scavenging; glutathione peroxidase/transferase substrate; Nrf2 pathway; melanin synthesis inhibition (tyrosinase) |
| Molecular Weight | 307.32 Da |
| Amino Acid Sequence | gamma-L-Glu-L-Cys-Gly |
| CAS Number | 70-18-8 |
| Half-Life | ~10-15 minutes |
| WADA Status | not_listed |
| Evidence Tier | Research Compound |
Mechanism Of Action
It acts as the primary defense shield inside every cell. It sacrifices itself by binding to toxic molecules, neutralizing their electrical charge so they can be filtered out by the liver safely.
Studied For
- Antioxidant therapy
- Detoxification / phase II liver detox
- Liver protection
- Skin brightening / whitening
- Oxidative stress reduction
- Immune system support
- Heavy metal chelation
- Aging and cellular senescence
- Mitochondrial protection
- Cancer adjuvant research
- Neurodegeneration models
- Alcohol-induced liver damage
- Athletic recovery and oxidative stress
- Drug toxicity protection
- Glutathione deficiency
- Cystic fibrosis models
- Parkinson's research
- Insulin resistance models
- Anti-inflammatory
- liver detox
- skin lightening
- immune support
- oxidative stress
- anti-aging
- cellular repair
Reported Research Findings
In vitro and animal data show robust cytoprotection. Human IV use reduced chemotherapy neuropathy in some trials. Oral bioavailability is low; wellness and skin-lightening IV claims lack controlled evidence.
Safety And Handling Notes
Generally tolerated short term. IV use can cause cramping and hypersensitivity; unregulated IV skin-lightening has been linked to serious harm. Inhaled forms can trigger bronchospasm.
Injectable glutathione is compounded and not FDA-approved; FDA has warned against injectable skin-lightening products.
Regulatory Status
Oral supplement; injectable is compounded and not FDA-approved.
Full Reference Detail
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This Reference Is Provided For In Vitro Laboratory Research Use Only. Not For Human Consumption. See The Full Research Disclaimer.