Technical Data Sheet
Glutathione
Also Known As: GSH, L-Glutathione, Reduced glutathione, Gamma-glutamylcysteinylglycine, Glutathione reduced, L-GSH, Glutathiol, Tathion, Isethion, Glutatione, Master antioxidant, Endogenous antioxidant tripeptide, GSH peptide, Liver antioxidant, Glu-Cys-Gly, master antioxidant
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| Evidence Tier | Research Compound |
|---|---|
| Category | Anti-Aging & Longevity |
| Class | Endogenous tripeptide (Glu-Cys-Gly); master intracellular antioxidant |
| Molecular Target | Reactive oxygen species scavenging; glutathione peroxidase/transferase substrate; Nrf2 pathway; melanin synthesis inhibition (tyrosinase) |
| Sequence | gamma-L-Glu-L-Cys-Gly |
| Molecular Weight | ~307.32 Da |
| CAS | 70-18-8 |
| Parent | Endogenous tripeptide |
| Mechanism | It acts as the primary defense shield inside every cell. It sacrifices itself by binding to toxic molecules, neutralizing their electrical charge so they can be filtered out by the liver safely. |
| Studied For | Antioxidant therapy, Detoxification / phase II liver detox, Liver protection, Skin brightening / whitening, Oxidative stress reduction, Immune system support, Heavy metal chelation, Aging and cellular senescence, Mitochondrial protection, Cancer adjuvant research, Neurodegeneration models, Alcohol-induced liver damage, Athletic recovery and oxidative stress, Drug toxicity protection, Glutathione deficiency, Cystic fibrosis models, Parkinson's research, Insulin resistance models, Anti-inflammatory, liver detox, skin lightening, immune support, oxidative stress, anti-aging, cellular repair |
| Administration Route | Injection Only |
| Form | lyophilized or solution |
| Diluent | sterile water |
| Storage Temperature | cold, dry, dark |
| Light Sensitive | Yes |
| Freeze / Thaw | avoid |
| Reconstituted Shelf Life | 14 Days |
| Handling Notes | Thiol oxidizes readily on air exposure; use fresh. |
| Regulatory | Oral supplement; injectable is compounded and not FDA-approved. |
| Sources |