Technical Data Sheet
Thymalin
Also Known As: Thymus polypeptide bioregulator, Thymalin peptide, Thymus bioregulator, Thymus extract bioregulator, Khavinson thymus peptide, Thymulin analog, Immune restoration bioregulator, Thymic polypeptide thymalin, Calf thymus extract peptide, Immunomodulatory thymalin, thymus extract, thymic bioregulator
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| Evidence Tier | Research Compound |
|---|---|
| Category | Anti-Aging & Longevity |
| Class | Polypeptide thymic bioregulator derived from calf thymus tissue |
| Molecular Target | T-lymphocyte differentiation and maturation; thymic hormones (thymosin, thymopoietin analog); IL-2 / IFN-gamma restoration |
| Sequence | Calf thymus low-molecular-weight polypeptide complex; not a single molecule. Constituent dipeptides include Glu-Trp (Thymogen / Oglufanide, CAS 38101-59-6) and Lys-Glu (Vilon, CAS 45234-02-4). |
| Molecular Weight | Heterogeneous mixture; roughly 80 to 90 percent of components fall between 600 and 6000 Da |
| CAS | 131183-11-4 (Thymalin, calf thymus polypeptide complex) |
| Parent | Calf thymus extract |
| Mechanism | It regulates the thymus gland, stimulating the production and maturation of T-cells, ensuring the immune system can correctly identify and destroy harmful pathogens without attacking healthy cells. |
| Studied For | Immunosenescence reversal, Immune system restoration in aging, Infection resistance enhancement, T-cell function restoration, Longevity via immune optimization, Age-related immune decline, Cancer immune surveillance research, HIV immune support models, Chronic infection models, Thymus involution reversal, Autoimmune modulation research, Antioxidant protection, Melatonin-thymalin longevity combination, immune regulation, anti-aging, T-cell function, longevity, viral infections, immune restoration |
| Administration Route | Injection Only |
| Form | lyophilized |
| Diluent | bacteriostatic or sterile water |
| Storage Temperature | frozen/refrigerated, dark |
| Light Sensitive | Yes |
| Freeze / Thaw | avoid |
| Reconstituted Shelf Life | 28 Days |
| Handling Notes | Short-lived constituents. |
| Regulatory | Used in Russia; not US or EU approved; research chemical. |
| Sources |