Technical Data Sheet
Kisspeptin-10
Also Known As: Kisspeptin, Metastin, KP-10, Kisspeptin 10, KP10, Metastin 45-54, KISS1 peptide fragment, Kisspeptin receptor agonist, GnRH pulse stimulator, Reproductive neuropeptide, Kisspeptin-10 acetate, KISS1R agonist, metastin
Scan To View Profile
| Evidence Tier | Investigational |
|---|---|
| Category | Sexual Health & Hormones |
| Class | Endogenous neuropeptide (KISS1 gene product fragment); GPR54/KISS1R agonist |
| Molecular Target | GPR54 / KISS1R on GnRH neurons in hypothalamus; stimulates LH/FSH via pulsatile GnRH release |
| Sequence | YNWNSFGLRF-NH2 |
| Molecular Weight | ~1302 Da |
| CAS | 374675-21-5 |
| Parent | KISS1 gene product |
| Mechanism | It stimulates the hypothalamus in the brain to release GnRH. This sets off a natural chain reaction down to the pituitary gland and reproductive organs to boost natural hormone production. |
| Studied For | Reproductive axis research, LH/FSH stimulation, Fertility treatment, GnRH pulse regulation, Hypogonadotropic hypogonadism models, Male testosterone stimulation, Female ovulation stimulation, Pubertal timing research, Hormonal axis restoration, Hypothalamic amenorrhea models, Polycystic ovary syndrome (PCOS) research, Sexual maturation research, LH surge induction, Spermatogenesis support, HPA-HPG axis interaction, testosterone boost, fertility, libido, HPTA restart, hypogonadism |
| Administration Route | Injection Only |
| Form | lyophilized |
| Diluent | bacteriostatic or sterile water |
| Storage Temperature | -4°F, dark |
| Light Sensitive | Yes |
| Freeze / Thaw | avoid |
| Reconstituted Shelf Life | 14 Days |
| Handling Notes | Oxidation-prone residues; protect from light. |
| Regulatory | Not approved; investigational / research reagent. Named on the WADA 2026 Prohibited List under S2.2.1 as "kisspeptin and its agonist analogues", a testosterone-stimulating peptide prohibited in males at all times; non-Specified. |
| Sources |