Technical Data Sheet
Ipamorelin
Also Known As: NNC 26-0161, NNC26-0161, Ipamorelin acetate, GHRP-1a analog, Selective GHRP, Ipamorelin peptide, Growth hormone secretagogue ipamorelin, IPA peptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2, Pentapeptide GHS, growth hormone secretagogue, GHS, ipa
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| Evidence Tier | Research Compound |
|---|---|
| Category | Muscle Growth & Performance |
| Class | Selective synthetic pentapeptide GH secretagogue (GHRP); minimal cortisol/prolactin side effects |
| Molecular Target | GHS-R1a (ghrelin receptor) agonist; highly selective for pituitary GH release without significant ACTH/cortisol elevation |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| Molecular Weight | ~712 Da |
| CAS | 170851-70-4 |
| Parent | Ghrelin mimetic |
| Mechanism | It is a highly selective ghrelin mimetic. It stimulates a clean pulse of growth hormone without accidentally triggering the release of cortisol (stress) or prolactin, making it incredibly well-tolerated. |
| Studied For | GH secretagogue research, Anti-aging / longevity via GH axis, Body composition improvement, Lean muscle gain, Fat loss via GH, Sleep quality / GH rhythm, Recovery, Bone density via GH, IGF-1 elevation, Pulsatile GH release simulation, Stacked with CJC-1295 (no DAC), GI motility research, Metabolic rate improvement, Collagen synthesis via GH, Athletic performance, anti-aging, muscle growth, fat loss, recovery, deep sleep, bone density, cellular repair, GH pulse stimulation |
| Administration Route | Injection Only |
| Form | lyophilized |
| Diluent | bacteriostatic or sterile water |
| Storage Temperature | cold, dark |
| Light Sensitive | Yes |
| Freeze / Thaw | avoid |
| Reconstituted Shelf Life | 28 Days |
| Handling Notes | Most selective GHRP; often paired with a GHRH analog. |
| Regulatory | Not FDA-approved; research chemical; WADA S2. |
| Sources |