Technical Data Sheet
HMG
Also Known As: Human Menopausal Gonadotropin, Menotropin, Menopur, Repronex, Pergonal, Humegon, Menogon, FSH LH blend, HMG injection, Gonadotropin blend, FSH/LH combination, Urinary gonadotropin extract, HMG fertility drug, menotropins
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| Evidence Tier | Approved Drug |
|---|---|
| Category | Muscle Growth & Performance |
| Class | Purified urinary extract containing FSH + LH gonadotropins |
| Molecular Target | FSH receptor (FSHR) on granulosa/Sertoli cells + LH/hCG receptor (LHCGR) on theca/Leydig cells; dual gonadal stimulation |
| Sequence | glycoprotein hormone mixture |
| Molecular Weight | mixture (~30 kDa subunits) |
| CAS | 9002-68-0 |
| Parent | Postmenopausal urinary gonadotropins |
| Mechanism | It provides a mix of FSH and LH, the two master hormones that directly command the reproductive organs to produce viable sperm cells or mature eggs. |
| Studied For | IVF / ART ovulation induction, Controlled ovarian hyperstimulation, Spermatogenesis support in males, Hypogonadotropic hypogonadism, Female infertility treatment, Male infertility research, Follicle development, Polycystic ovary syndrome (PCOS) research, LH + FSH combined stimulation, Fertility preservation research, Assisted reproduction research, fertility, spermatogenesis, LH/FSH, FSH, testicular function |
| Administration Route | Injection Only |
| Form | lyophilized + diluent |
| Diluent | supplied diluent; gentle swirl |
| Storage Temperature | per brand; refrigerate or controlled room temp |
| Light Sensitive | Yes |
| Freeze / Thaw | avoid |
| Reconstituted Shelf Life | 7 Days |
| Handling Notes | Use promptly after reconstitution. |
| Regulatory | FDA/EMA-approved Rx; WADA-prohibited in males. |
| Sources |