Technical Data Sheet

Thymosin Alpha-1

Also Known As: Thymalfasin, Zadaxin, Talpha1, Tα1, Thymosin alpha 1, Thymosin α1, Thymalfasine, Hepatitis thymosin, Immune adjuvant thymosin, TA1, Zadaxin thymosin, Thymosin alpha-1 acetate, Prothymosin fragment, Hepatitis B immune peptide, TA-1, thymalfasin

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Evidence Tier	Approved Drug
Category	Immunity & Wellness
Class	28-amino acid peptide; N-terminal fragment of prothymosin alpha; biological response modifier
Molecular Target	TLR2/TLR9 signaling; dendritic cell maturation; T-helper (Th1) polarization; NK cell cytotoxicity; NF-kB immunomodulation
Sequence	Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH
Molecular Weight	~3108 Da
CAS	62304-98-7
Parent	Prothymosin alpha N-terminal fragment
Mechanism	It directly stimulates the action of natural killer cells and T-cells, enhancing the body's cell-mediated immune response to quickly hunt down and eradicate viral infections and rogue cells.
Studied For	Chronic hepatitis B treatment, Chronic hepatitis C treatment, Cancer immune adjunct therapy, Vaccine adjuvant, Sepsis / severe infection, COVID-19 immune support research, Immunodeficiency models, HIV / AIDS immune support, Antifungal immune support, Malignant melanoma adjuvant, Lung cancer immune research, T-cell / NK cell activation, Dendritic cell maturation, Toll-like receptor signaling, Autoimmune modulation, Gut mucosal immunity, Chemotherapy immune protection, immune booster, T-cell modulation, viral infection, autoimmune, immunomodulator, Lyme disease, chronic fatigue, cancer adjunctive, vaccine efficacy
Administration Route	Injection Only
Form	lyophilized
Diluent	supplied or sterile diluent
Storage Temperature	refrigerate 36-46°F, dark; do not freeze the formulated product
Light Sensitive	Yes
Freeze / Thaw	avoid
Reconstituted Shelf Life	14 Days
Handling Notes	N-acetyl group aids stability.
Regulatory	Approved as thymalfasin in 30+ countries; not US central-approved.
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