Technical Data Sheet
Sermorelin
Also Known As: GRF 1-29, Sermorelin Acetate, Geref, Gerel, GRF(1-29)-NH2, Growth hormone releasing factor 1-29, GHRH 1-29, Natural GHRH analog, Sermorelin diagnostic, Sermorelin anti-aging, Sermorelin GHRH peptide, Growth releasing factor, GH stimulation peptide, GHRH 1-29 amide, GHRH, geref
Scan To View Profile
| Evidence Tier | Approved Drug |
|---|---|
| Category | Muscle Growth & Performance |
| Class | Synthetic 29-amino acid fragment of endogenous GHRH (GHRH 1-29-NH2) |
| Molecular Target | GHRH receptor (GHRHR) on anterior pituitary somatotrophs; stimulates endogenous GH gene expression and release |
| Sequence | GHRH(1-29) amide |
| Molecular Weight | ~3358 Da |
| CAS | 86168-78-7 |
| Parent | Growth hormone releasing hormone |
| Mechanism | It provides the shortest active sequence of Growth Hormone-Releasing Hormone (GHRH), binding to the pituitary to trigger a completely natural, mild pulse of growth hormone during sleep. |
| Studied For | Pituitary GH-reserve diagnostic, Pediatric GH deficiency (historical), Adult GH-axis / anti-aging research, GH secretagogue research, IGF-1 elevation, Body composition / lean mass, Fat loss via GH axis, Bone density support, Sleep quality via GH, Recovery and repair, GH deficiency models, Metabolic rate improvement, Collagen synthesis via GH, Anti-aging longevity research, GH replacement alternative, anti-aging, growth hormone secretagogue, sleep improvement, vitality, body composition, pituitary health |
| Administration Route | Injection Only |
| Form | lyophilized acetate |
| Diluent | sterile diluent |
| Storage Temperature | cold, dark |
| Light Sensitive | Yes |
| Freeze / Thaw | avoid |
| Reconstituted Shelf Life | 14 Days |
| Handling Notes | Short-lived solution; use promptly. |
| Regulatory | Was FDA-approved (withdrawn for commercial reasons); now compounded Rx; WADA S2. |
| Sources |