Intranasal Peptides: Which Research Compounds Are Studied As Nasal Sprays
Not every peptide can be delivered through the nose. Nasal absorption favors small molecules, so the question is decided mainly by molecular size and by whether real research exists for the nasal route. Below, every compound in the catalog is graded by the strength of that evidence. This page is for laboratory research reference only and is not medical or dosing advice.
How To Read The Tiers
An approved or registered nasal product exists, or there is solid human clinical or research use via the nose. These are the genuine nasal-instead-of-injection candidates.
Real published intranasal research exists (often animal models) or there is a strong size and mechanism rationale, but it is not yet a standard, validated human route. Promising, not proven.
Injection is the established route in practice. The compound is either too large to cross the nasal lining, has no credible nasal evidence, or its validated route is injection.
A nasal spray being sold somewhere is a marketing decision, not proof the route works. Several compounds are sold as sprays online while resting only on animal data or anecdote; those sit in the Emerging tier, not Established.
Important: The GLP-1 Weight-Loss Peptides Are Not Nasal-Viable
Semaglutide, Tirzepatide, Retatrutide, Survodutide, and Cagrilintide are all large acylated peptides (roughly 4,100 to 5,000 Da). They are injection compounds in practice, and any nasal-spray version sold elsewhere has no validated absorption data. Do not assume an injectable GLP-1 can be swapped for an equivalent nasal spray.
Established Nasal Candidates
Approved or registered nasal products, or solid human clinical use. Select any compound for its full research profile.
Emerging Nasal Candidates
Real but preliminary intranasal research, not yet a standard human route. Injection remains the established route for these.
Injection-Only Compounds (61)
The remaining catalog compounds are studied via injection in practice, because they are too large for nasal absorption, lack credible nasal evidence, or have injection as their validated route. Each compound's research profile and spec sheet shows its administration route.
Selected Sources
Research Use Only. Not For Human Or Veterinary Use. Information Provided For Laboratory Research Purposes Only.